Kleenex Anti-Viral Tissues are the only tissue that can kill 99.9% of cold and flu viruses*, helping you to take care of you and your family during cold and flu season. Made with 3 soft plies, including a moisture-activated middle layer that kills 99.9% of cold and flu viruses in the tissue*. *Virucidal against: Rhinoviruses Type 1A and 2 (Rhinoviruses are the leading cause of the common cold); Influenza A and Influenza B (causes of the flu); Respiratory Syncytial Virus (RSV – the leading cause of lower respiratory tract infection in children)