Relieve your cold and sinus symptoms with extra strength Tylenol® Cold & Sinus daytime/nighttime caplets. Each caplet contains 500 mg of acetaminophen for pain relief and 30 mg of pseudoephedrine hydrochloride for nasal congestion relief. The nighttime caplets add 2 mg of chlorpheniramine maleate for relief of runny nose and sneezing and lets you rest. These caplets relieve nasal congestion, sinus pain and pressure, headaches, and fever during your day and night.